There are 52 mathematicians whose last name begin with SPO.
| Spoar, Gary | McMaster University | 1971 |
| Spodarev, Evgueni | ||
| Spodzieja, Stanislaw | ||
| Spoelder, Hans | Vrije Universiteit Amsterdam | 1987 |
| Spoelstra, Jacob | University of Southern California | 1999 |
| Spoelstra, Margreet | Technische Universiteit Delft | 2000 |
| Spoelstra, Nyle | University of Wisconsin-Madison | 1969 |
| Spoelstra, Titus | Universiteit Leiden | 1972 |
| Spoerel, Detlef | Technische Universität Carolo-Wilhelmina zu Braunschweig | 1978 |
| Spoerhase, Joachim | Bayerische Julius-Maximilians-Universität Würzburg | 2010 |
| Spofford, Charles | ||
| Spognardi, Angelo | Università di Roma La Sapienza | 2008 |
| Spohn, Andreas | ||
| Spohn, Herbert | Ludwig-Maximilians-Universität München | 1975 |
| Spohn, Karen | University of Delaware | 1998 |
| Spohn, Meta Lina | ETH Zürich | 2023 |
| Spohn, William | University of Pennsylvania | 1962 |
| Spohn, Wolfgang | Ludwig-Maximilians-Universität München | 1976 |
| Spohr, Christopher | Massachusetts Institute of Technology | 2000 |
| Spohrer, James | Yale University | 1989 |
| Spoida, Peter | University of Oxford | 2014 |
| Spokoiny, Vladimir | Lomonosov Moscow State University | 1987 |
| Spolaor, Luca | Universität Zürich | 2015 |
| Sponagel, Stefan | Technische Universität Darmstadt | 1982 |
| Spönemann, Claudia | Gottfried Wilhelm Leibniz Universität Hannover | 1988 |
| Spönemann, Miro | Christian-Albrechts-Universität zu Kiel | 2015 |
| Spönemann, Uwe | Universität Bielefeld | 1997 |
| Spong, Matthew | University of Melbourne | 2019 |
| Sponselee, Annemie | Technische Universiteit Eindhoven | 2013 |
| Spoon, Alexander | Georgia Institute of Technology | 2005 |
| Spoon, Henrik | Rijksuniversiteit Groningen | 2003 |
| Spoonamore, Janet | University of Illinois at Urbana-Champaign | 1992 |
| Spooner, Chad | University of California, Davis | 1992 |
| Spooner, David | University of Calgary | 1998 |
| Spoonhower, Daniel | Carnegie Mellon University | 2009 |
| Spoonhower, John | Cornell University | 1977 |
| Spoor, François | Technische Universiteit Delft | 2018 |
| Spoor, Peter | Technische Universiteit Eindhoven | 2002 |
| Sporer, Benedikt | Eberhard-Karls-Universität Tübingen | 1896 |
| Sporer, Mathias | Technische Universität Chemnitz | 2007 |
| Sporis, Ligia | University of Bucharest | 2001 |
| Sporn, Femke | 2023 | |
| Sporre, Göran | Kungliga Tekniska Högskolan (KTH) | 2003 |
| Sportisse, Bruno | École Polytechnique | 1999 |
| Sportsman, J. | University of Illinois at Urbana-Champaign | 1987 |
| Sporyshev, Piotr | St. Petersburg State University | 1984 |
| Sposito, Vincent | Iowa State University | 1970 |
| Spoto, Edmundo | Universidade Estadual de Campinas | 2000 |
| Spott, Martin | Karlsruher Institut für Technologie (KIT) | 2000 |
| Spotti, Cristiano | Imperial College London | 2012 |
| Spouge, John | University of Oxford | 1983 |
| Spourdalakis, Aris | University of Toronto | 2022 |